preprint: Cohesin-mediated chromatin remodeling controls the differentiation and function of conventional dendritic cells
Does chromatin organization shape immune responses? Our recent study with Nick Adams led by Reizis Lab and Leonid Mirny explores how cohesin, a key player in chromatin loop extrusion, controls the chromatin architecture essential for conventional dendritic cells (cDC). DCs bridge innate and adaptive immunity. Surprisingly, strictly required factor for DCs to function is cohesin. […]